Sounds like the F1x would do well, but with a different layout than you're used to. I use mine with the 720-230 3-compartment insert and keep the 70-200 in the back right corner; a 12-24 in the middle compartment and the 5d3/24-70 in the back left compartment. The end pockets nicely take up to a 600EX (in Canon's pouch) with OC-S3 cord and RRS WPF flash bracket in each. Then the 7D on edge with the 100-400 mounted (and resting on a couple of boxes of batteries - both LP-E6s and AA cells); if your body is gripped, there's room for the grip at the end of the 730-230. And the front pockets, lid zip pocket, back pocket and mesh pockets all help organize small stuff. For that matter, with Tiffen's move to using movable dividers in their inserts, you could probably use the stock insert to hold the lenses and keep the body with 24-70 in the remaining space; the flash in an outside pocket still. Won't hold most laptops, but a tablet would fit in the back zip pocket.
Thanks for the info. The hardest part is that the camera store selection is very limited around here. I think the closest one is over an hour a way. Well, there is another closer but they don't carry much, are over priced, and focus mainly on printing. Trying to pick a bag from internet reviews and pictures sucks. I found the first one I was talking about carries Domke, so I may go check them out.
The 7MDH is also my primary carry, normally with my 6D and either the 70-200 or 16-35 attached in the center (sometimes gripped) and the 100L in the back right. Sometimes I'll carry all three (with the third in the front left), but that gets heavy on one shoulder. Also in the bag is a 600EX-RT in the back left. A Giottos blaster and sometimes the 40mm Pancake in the front right and at least one extra battery in the center back. Shutter release in the flap pocket and assorted small items in the front pocket.
I find this setup ideal and do not long for any other bag. I do not find the padding to be inadequate at all, on the bottom or inside. Inside the little flip up padded tabs seem to isolate most everything. I think if you'd center the middle compartment for your body with long lens (or UWA) attached you will learn to love this bag as I have. I love my Crumpler products. Quality made stuff and very user friendly.
Don't get me wrong, I do like my 7MDH. The padding I found a problem with though was on the bottom of the bag itself and with the lenses pointed down, it feels like they sit down hard. Maybe because it's probably almost 7 years old. I also have the MK I which has very limited extra storage. The front pocket and the inside lid pocket are it and the mesh isn't ideal. I had a vivitar sync cable scratch a nice gouge in to my 5D MKII in the first week of owning it because the point came through the mesh.
Plus my girlfriend calls me a bag whore. I think she may have a point when it comes to camera and laptop/school bags. "D