Just spent last night wandering the streets of Portland with the bag, my 5D II (with grip and RRS L bracket), Zeiss 50 1.4, 17-40, 24-70 and 70-200 f4 L in it. Also had room in one of the front pockets for a gore-tex rain shell and the wife's wallet. Very comfortable to carry, easy access to the lenses and does not look like a camera bag. Left the 70-200 on the body and lens down it fit nicely in the bag. Could easily exchange the 70-200 for the 100-400 (and thus the 70-200 2.8) and have it fit in the bag. Could easily keep 2 bodies with grips and lenses attached in this bag. I'll measure the interior later today and see if I can fit a 13" MacBook (not pro) in the bag.