My issue might be usable focus point with certain lenses? So does that mean if I have my AF point on my 85mm f/1.2 lets say all the way to the right of the frame that my sharpness will be off? So i will have to focus center of frame and recompose the shot?
I'm afraid you are rather missing the point! If everything else is in order....MFA etc. ...then the camera will begin to focus on the point you set, whether it's in the centre or to the far right or left. That is the whole idea of the excellent new systems in the 1DX and 5D3. After achieving focus on the chosen point, and depending what "case" you are set on, and how many focus points you have chosen to use, the camera will follow the subject you focussed on until you shoot, or until circumstances change sufficiently for it to lose focus.