I just recently got this lens for my 5Diii. I use single point AF or single point spot AF placed on the eye, usually the center point. Its definitely worth the time to test and set the micro-focus adjustment. I currently use a setting of +3 to correct some front focusing. That said, my miss-rate is still frustrating. If you have the patience for it, live view autofocus is rock solid.
I think a big part of my problem is that I'm shooting wide open at close distances, so my depth of field feels like its approximately 2-3 microns, and if it doesn't land exactly where I want it to (the eye usually) it feels like a failed shot. I should probably back up or stop down. But I never seem to want to.