I use LR mostly for ecommerce/catalog stuff, and anything else I use PS. Lightroom took a while to get a handle of, but after a couple months I felt fairly comfortable incorporating it into my workflow. It's really just quicker to edit multiple files the way I need to with LR. With PS I can do more detailed work (ex. beauty, lookbooks, magazine shoots, etc) and use more complex methods like channel masking, split freq. retouching, etc.
I tried Capture One Pro, and loved the RAW conversions but couldn't figure out how to use it effectively or quickly. Gave up by the time the trial was over, but might revisit one day when I have more time.