They are either very compliant or never stop moving at light speed. Auto iso is what has killed 10's of thousands of images in the last year.. The bummer wheel made it impossible to expose correctly.
When it comes to wildlife the light verys so much its about impossible. Its a bad habit to break. although setting iso 800 would have pushed your speed up a far bit dialing in a ton of EC.
Best I ever got was a super cool mink that came across a pond over logs and up a rocky hill to come sniff my boot. I tried to shoot that but only got bits and peaces as he came to me.
Never try this with a 100-400mm