A couple of points: 1) There are soft copies of the 100-400. My photos have always been soft even using what I believe to be good technique. I finally decided to test mine in controlled conditions (tripod, live view, 10x, wireless remote, both AF and MF, etc., etc.) across a lot of focal lengths and apertures. Every photo was equally soft. I finally sent it to Canon this morning for alignment. 2) Set up your camera on your tripod at 400mm with live view at 10x and without touching the camera, notice how much movement you see in the viewfinder. Unless you have a very stable tripod, you can still get significant movement. I have a lighter travel tripod, and when I observe that kind of movement (e.g. on a windy day) I turn the IS on even using the tripod. And I always use a wireless remote when using the 100-400 on my tripod. 3) In the older models like I have (not sure about newer ones) the IS kind of clunks in and you can see it freeze the frame - so you know it's working or not.