I would say 1000 flashes an hour, the flash unit would be the week link. Even at reduced power that's a lot of heat. It would also require several battery changes I suspect. My guess is the circuitry in the pack would tend to overheat as well under those conditions. There is a transformer in the pack to get the high voltage and they generate heat.
That kind of workload, a shot every 3.75 seconds on average seems well beyond what the 580EX and pack are intended for.
This is why I work with 2 flashes and sub them out once in a while... but it still doesn't change the fact that the flashes are in for a serious a$$-kicking. If you've ever seen someone on the side of a race course with a camera and flash this is what we are doing. The batteries get too hot to touch... but through 2 seasons my 580exII has stood up well. Sometimes the thermal controls in the flash "force" a cool down period... but it has not burned out. I also have an old 540EZ that I use (same plug for external battery power) and it has stood up to even more races... I just need a battery pack that can keep up with the flash


