My understanding is that "focusing by wire" is done for those lenses, where for internal focusing to work well you have to move many groups of lenses around, with different pace, which make mechanical focusing impossible (or too complicated).
Nope, There is no many groups, just single one.
EF 300 2.8L USM is focus-by-wire, while IS version is not.
Making USM to manual focusable, all it needs is a clutch between USM ring and manual focusing ring.




