Well, there are various things that can affect a 100% crop and, of course noise from an image that can show up noticeably when either a High ISO was used or areas that have had the brightness boosted is one of those issues -- if, rather than enlarging the 100% crop to "full size" you reduce full image to post on the Web or you print at a size that doesn't "simulate" a 100% crop, then the noise will tend to be "drowned out" -- it's in the original image, but it doesn't look bad at all in the reduced image. It has less to do with whether you are starting with a full frame image or not -- the links you posted there were about the 7D, not a full-frame body. In fact, as a rule full-frame sensors tend to produce images with less noise-per-pixel, but that's another discussion.
But, to me the other most practical concern is simply that a closely cropped image has less usefulness when it comes to displaying/printing. I can take a 100% crop and print a nice 4x6 or 5x7 print from it, and since such prints are so undemanding, and because the resolution "needed" for decent quality is not far from the resolution of a 100% crop, then I'm not fussed about that. But, when you get to, say, an 8x10 print, then you start to notice thngs. Noise and softening of detail will become apparent with an 8x10. And that matters to me because an 8x10 is to me a "coffee table" size -- show to guests and they will pick it up and look in a way that will be at least as bad as you viewing the 100% crop on your monitor. So, if I look at a close crop on my monitor, if it looks bad at a 100% view, well, I have no use for that.
A few days ago I used my macro lens to chase some little flies around on my deck. They were so little that unless I got really close the shots would require a 100% crop to look like any kind of composition. I used a tripod, but still the skitterish critters kept flying away, so getting to the "full macro" closeness was, well, a pretty tough and frustrated exercise. So, did I get any "keepers"? Well yeah, although I've yet to process them for any kind of output. But, they all look best, like I said, as 100% crops, dang!
Also, I did some "Shooting the Moon" sessions for six early mornings last week, using my 100-400 lens with my 1.4x TC, so 560mm of "reach" mounted on my 1DM3 on a tripod, and using a cable release to minimize camera shake, all to maximize sharpness, and that knowing well that first, using a converter on a lens like that will not give the sharpest results, and second, knowing that even with 560mm of focal length, the moon will still be a "little ball" in the "big sky", and to come out with a "decent moon shop image", well, yes, I would need to crop "a lot"...
Well, here are a couple of those crops:


Not so bad, all the above considered, and I'd say they would put out a nice 8x10, since moon shots show a lot of noise unless you are somewhat sloppy and they respond well to sharpening. And, hanging on my wall beside me is a 12x16 print of a moon shot, a lot like these, and it looks pretty good, but I'd say it is pushing the limit in terms of softening of the detail. It looks fine hanging on the wall a few feet awy, but it softens when you get up closer. And, I would not likely be printing it poster-size. Hmm...