@cybercat, so what kind of settings are typical of what you shoot, because we have some shots in this thread that are in quite low light, all the way to the point the AF starts to give up the ghost?
Remember that low light is not the only reason one would need high iso values. Also, the different settings and techniques outlined here help with ANY exposure (or any body really), whether super low light or otherwise, it doesn't really matter you shoot in venues at "lower" exposures than what you see here (even though I have examples either here or elsewhere where I am shooting at 1/15th at f2.8 at 3200, which is nearly so dark, you cannot make out details of objects.
You are right, I forgot to mention that I shoot cat shows indoors usually without any natural light. Only artificial light not on full power as that makes the rooms too warm.
I need to keep the shutter speed at 1/125 or faster to minimize motion blur from the fact that cats are animals and moving.
So low light and relatively faster shutter speeds - that is why I need high ISO.
Here is an example how noisy it gets for me at ISO 1600.











