My flash would lose connection when I pointed my 1Ds2 downward. I noticed the my flash would move left to right just a little bit. So, I thought something was wrong with the flash. Then, I took the flash off, looked at the hotshoe and then I tried to lift up on it and sure enough, the right side would lift up just a tiny bit. So, I slid the clip off, tightened the two loose screws on the right side, and the problem was solved. The clip will slide backwards, towards the eye cup when it comes off. You just needs something thin enough to get under the front of the clip (the front side of the camera). Once you slid it off there are four screws and you just need to tighten then. You will need a jeweler's Phillips head screwdriver because standard screw drives are NOT small enough.
If the screws are not loose, then there must be a problem with the flash.