For wildlife around Banff, take Highway 1A aka the Bow Valley Parkway. It parallels the Trans Canada, so it will take you from just outside Banff to Lake Louise. I did some camping recently in Banff and Jasper and that road is where we saw the bulk of the wildlife. Bears, deer, big horn sheep were the most frequent.
My experience was opposite, I saw next to no wildlife on the apparently extremely wildlife packed Ice Valley Parkway, nor did I see any in Jasper.... But that was my luck. For the wildlife on Bow Valley Parkway a 300 is going to be a good lens. Youll be amazed how close they are to the road. I bought a 100-400 for my trip and a lot of my wildlife shots were in the 300-350 range. Some were even less, 100-200 range. They do get very close. Drive it in the mornings and late afternoon/early evening for best chances to see some.
Count on a long drive up the Ice Valley Parkway. There is lots to stop and take pictures of. Very scenic and beautiful.
Johnston Canyon Falls trail is on the Bow Valley Parkway. This is a nice hike BUT if you want to hike it you must start early. It is one of the most popular trails in Banff and Jasper and gets VERY busy. Has some nice waterfall shots and opportunities for ND filters for milky water but space can be tight for tripods with all the crowds. There are railings to set your camera on which can actually get you some nice shots of stuff so dont worry too much. You can see the waterfalls and go all the way to the Ink Pots which are apparently a neat site (I didnt see them due to timing and the crowds, my girlfriend and I arent much for hiking in crowds).
Lake Louise has some trails around it too. Again very busy and popular. The Tea House trail is steep but offers some nice views of the lake and mountains. Depending on your endurance level you can go all the way up to the Beehives for some views from those mountains.
Athabasca Falls is a great stop for later in the day when the sun is low. Light is somewhat harsh at mid day.
Tangle Creek Falls is a nice waterfall stop but its at the side of the road and very busy.
Moraine Lake on the Rock Pile at sunset is a must do, even multiple times. Also a must do if its stormy looking, theres some great views from the Rock Pile.
Sit down now and console yourself with a few beers that you wont see everything you want to 
I cant help you on the Clearwater area, I took a different route to Banff and Jasper.
Ill say it now since it fits in your itinerary. Vancouver doesnt really have a zoo with mammals, so if you want to see some stop in the BC Wildlife Park in Kamloops. Its part zoo and part wildlife rehab. Its not really like most "true" zoos though, its quite geared towards wildlife rescue and such. BC Zoo
Your itinerary said Clearwater then Whistler. I would suggest avoiding Highway 5 to Vancouver and going straight to Whistler via the 99.
Highway 99 to Whistler
This will help you avoid some traffic and take the scenic route into Whistler. Check road reports before leaving though, this road can be blocked by rockslides, accidents, Albertans confused by a road curve, or construction. Its not a wide or fast highway but a great drive.
Theres lots to do in and around Whistler. Take the Peak to Peak Gondola for sure.
Cant help much on Tofino, never been there myself. Heard its amazing though.
Victoria is nice, dont expect a big city feel like Vancouver though. The Royal BC Museum is a great place to go.
http://www.royalbcmuseum.bc.ca
Vancouver is a great place, plenty to see and do. Stanley Park for hiking, views and the BC Aquarium. Granville Island for views and food. Gastown for Vancouver's history and past. Check out the Steam Clock. There is also a statue that explains how Gastown got its name. Its probably not what you expect. The answer can be found on Wikipedia but thats less fun.
If you have a car drive up to the Cypress Bowl Road to the viewpoint thats mid way up (cant miss it). Great in the evening and at sunrise or sunset.
Science World is a fun visit.
f you are into hiking, Vancouver has a huge number of trails. If you post what your skill level is I can suggest a few to match if you want.
Youll have to post what kind of food you like as Vancouver has pretty much any kind you can think of. If you like Indian, there is a place called Vijs that is world class but very busy. Make a reservation. Make sure you have some ceder plank smoked Salmon, Granville Island has some good places for that.
Grouse Mountain is also a fun visit. There is a large gondola that goes up to the top. There is no road, only the gondola. There is also the Grouse Grind. This is a hike up the side of the mountain to the top. Its quite a workout and supposed to be one way only (UP). You get a discount ticket at the top for the gondola down. Depending on your fitness level this is one of the quintessential Vancouver things to do. Things to do up top vary on time of year but there is stuff at all times. The gondola itself is fun, there is hiking or skiing and snowboarding up there. There is also a large wind power station up there and it has its own viewpoint.
Grouse Mountain
Capilano Suspension Bridge, also has some hiking trails and other stuff.
Capilano Suspension Bridge
Edit: Dont forget the power converters and a Metric conversion app for your phone.
Mind if I ask where you're staying in Tofino and what time of year? 
