If you are on Adobe, Nvidia GPUs are the only real choice. 500 or 600 series (400s run quite hot and are being phased out). Or Quadros if you are doing serious 3D work. (True, the Nvidia issue is less critical if you are not doing video (right now), but why bother handicapping yourself right from the get-go? Times change, and clients and software only get more demanding.)
I am running a moderately overclocked 2600k on the stock cooler. I was waiting for the mounting brackets for my V8 when I built it, but haven't bothered to install it as the temps are fine and it runs CS5 (PP) like a champ without having to push the overclocking. The stock cooler is not the most confidence-inspiring looking thing in the world, but as I'm not into fiddling around with my computer all the time the V8 will have to wait until I need to do something inside the case.
I was worried about Gigabyte but I heard they are really good now so I took a chance with this computer but went higher end rather than lower as the components tend to be better and the extra features can (and did) come in handy. Overclocking the 2600k took about 1 minute on the Gigabyte motherboard- they've come a long way. And two 2-drive RAID 0s, one 2-drive RAID 1, one OS/apps drive (plus 2 more for the hackingtosh) on the on-board controllers run flawlessly and took no time at all to set up. (And without having to invest in a RAID card.) I'm not into benchmark p***ing contests, but I did run PPBM5 when I built it and it was seriously fast even though I was running all my normal crap.
I spent way too many years as a starving artist, so I've spent way too much time over the years (decades) futzing around trying to make cobbled-together or out of date computers do what I need. This was my first ground-up build and it was incredibly simple. And big cases with good, quiet cooling and lots of drives make life easy, back ups less of a pain, and processing fast.


