Using the acrylic spray prevents most of the ink from running. Products like Krylon Crystal Clear Acrylic are acrylic based.
While I, personally, have not used Krylon on inkjet prints, I certainly have experience in spraying Krylon protective sprays on conventional photographic prints, and my father used to use it on his charcoal charictures.
From Mastering Digital Printing by Harald Johnson, "Coating brands that have developed followings with digital printers include the following: Clearstar ClearShield and ClearJet (clearstarcorp.com) Superfrog Frog Juice (superfrog.com) Lyson Print Guard (Lyson.com), Bulldog Ultra Coating (bulldogproducts.com) Liquitex Solivar varnish, Krylon Crystal Clear, UV-CLear acrylic sprays, and Sureguard (perfectiondistruibuting.com), and Lacquer-Mat (Lacquer-mat.com) photo lacquers."