I just bought the 180 over the weekend. I do like it, though I haven't fully formed an opinion yet and was planning on posting a review after putting it through its paces.
Like you, I'm a fan of Lowepro's stuff. What I can tell you:
- Looks great
- Very well-made
- Lots of pockets, pouches, and places to store gear
- Excellent protective padding
- Comfortable padded strap
- Handy top handle
- Easy to remove/put away gear
- Front flap features large velcro fasteners and uses magnets when in "quiet mode"
The main compartment has two full length vertical dividers, effectively creating three sections, and two smaller horizontal dividers.
The bag will accommodate a pro body with grip and 70-200 attached in the main compartments plus four smaller primes, or four smaller zooms, or two more 70-200 in the side sections. You'd likely have room left over for one or two flashes in the side sections and a second pro body in the front pocket, but it'd be tight and uncomfortably heavy.
I'm happy with the bag thus far. Standby for a full review.