I have two main lenses I use for macro, the Tamron 90 and the MP-E65.
With the tamron I am sure if there is a foucs problem on a shot then it is down to me.
100% crops of 1:1 images taken on the Tamron/450D are sharp.On the MP-E, at lower magnifcation, the same applies.
At higher magnification the MP-E shots do not look good when cropped.
This is the non-cropped picture taken at 5x of a kitchen knife.
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The crop looks better than most of my shots, but still looks less than clear.
IMAGE LINK: http://www.flickr.com/photos/basandrews/6964335219/
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In comparison, using the same camera and lens but at 3x, the 100% crop of a spider leg is acceptible.
IMAGE LINK: http://www.flickr.com/photos/basandrews/6964335003/
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