I bought the Sigma 150-500 OS, and was somewhat unimpressed... so i moved up (price-wise) to the 300 f/4L IS. I already owned the Sigma 1.4x and 2x TCs. They work great on my 70-200 f/4L IS, and the 1.4x works great on my EF 100 2.8 Macro USM, but i'm not real happy with them on the 300. AF hunts a lot, is slowish, and some softening..and hefty PF (which is there in smaller amounts, with the bare lens anyways).
If i could afford it, i would grab a 1.4x TC II. Otherwise, i got what i wanted.. 400mm, f/5.6 with AF.. and IS, light and compact, and not too expensive. It's a great insect and flower lens as well, and being able to take shots at 1/125 and 1/100 handheld is sweet. For BIF, i would think the 400 5.6L would be the ticket.