I have a Sigma 50 as stated and was finding that it does miss focus from time to time. After extensive testing I narrowed the majority of the miss focused shots down to when I use spot/center focus with my 7D. Since I happen to run a surfacing/coatings department for a lens manufacturing company I took my Siggy to work and decided to get a better look at what was going on with the glass itself.
The short story is there appears to be a defect that is located almost dead center in the front element. It appears as a line about 10mm and has a ~~\__ look to it. My best guess, without actually removing the front element is either that it's a generator mark from a bad diamond/cutter or a bad mold from the manufacturer. If it is in fact a generator or mold issue this same defect could appear in many other lens of this type so it is something that should be checked for by us end users from now on.
I sent the lens to the Sigma Service center in New York and explained what I was seeing in both verbal and written form so the issue could be addressed. I received the lens back from them last Friday and the only remark they left was that they made adjustments for front/back focusing issues. I checked the lens for the defect and sure enough the defect is still there so they chose to ignore my request to replace the front element or even acknowledge it is even there. Needless to say it is going back and I will be talking to a manager this time about it.
If anyone has the inclination to check their lens for the defect as I described all you need to do is hold the lens under a fluorescent light and look for a break in the reflection as you rotate the lens. The defect in my lens can be seen when held at about a 30 degree angle and about 4-6 feet from the light in normal room lighting conditions.


