Sharp non-centered subjects?

It all depends on composition, camera and lens. Cameras have AF points at different locations across the frame and different numbers of cross-type AF points. Better lenses have sharper side/corner sharpness. What camera and lens are you using?

"I remember once someone saying if your aperture is very low then use the centre point because it will be more accurate. Can anyone verify this or not?

Unfortunately it seems to be kinda catch 22 because in those situations focus and recompose is even more tricky due to the shalIow dof."

It IS a catch 22. With DOF in the 1-2-3 millimeter range, recomposition is very likely to move that thin "plane" off the intended point due to changing the angle of the camera from the original, or unintentionally changing the distance.

As for the accuracy of the outer points, my 5Di &ii's outer points have a poor reputation for accuracy. I have no f/1.2 lenses. But with my fastest lenses, I have good results using the outer points with slight recomposition- much better than recomposing more drastically from the center point- and the "S" screen allows me to see what I need to see as far as the actual DOF and where sharp focus actually is.

ed rader wrote in post #14969866
i make the subject align and crop, if necessary.

I guess we all have to compromise somewhere.