sapearl wrote in post #15304588
When you save something for web, the file is being saved at about 72dpi which is great for email, FB, and galleries, but it will make a poor, low rez enlargement.
Bollocks.
ppi is entirely irrelevant here. It's merely a calculation aid. All that matters is file size in pixels.
http://www.scantips.com/no72dpi.html
All that's different in "save for web" compared to "save as" a jpg, is that it
- gives you a preview of what an image might look like in various types of browsers/color management used
- gives you the option to save a file at a certain file size (in kB)
- can strip all metadata from the file for minimal file size
- has a different user interface
- offers some other file types besides jpg and "animation" options.
It's not designed to save an 2400x3000 pixel file, but it can.
sapearl wrote in post #15304588
You want a large JPG, something at least 1MB which will make a very nice 5x7 and probably a decent 8x10.
Filesize of a jpg in MB depends on a lot of things, filesize in pixels only being one of them…
sapearl wrote in post #15304588
Now if something is coming out in print at Staples as too dark, that is a monitor calibration problem. His monitor is set too bright, so when he post processed the image he darkened it, which made the output even darker when Staples printed it. If you want make prints on a regular basis you will want to get your own monitor calibrated.
Good advice.
alphamalex wrote in post #15304561
How should I save the RAW as a JPG (or something else) so it turns out OK for printing?
Save as a jpg, not too low quality (In the "Save as" dialog about 8-10, in the "Save for Web" (if for whatever reason I cannot fathom you prefer that) about 80% or so.
You want the file to have about 240 to 300 pixels for every inch of paper, so 1200x1800 for a 4x6 or about 2400x3000 for an 8x10". Note that I did not mention any ppi setting, because it is irrelevant.
Just to avoid confusion, you might ant to set 300ppi. Also saves you fromhaviong to do the math 
Use sRGB unless both you and the lab understand color management.
alphamalex wrote in post #15304561
The reason I ask is that I gave a co-worker some JPGs (exported the same way) for a personal calendar which he had printed at Staples online and they turned out dark and maybe a tad over saturated.
He should calibrate his screen. And so should you.
Using a calibrator is the most accurate way, but you can workaround a bit (as dmward mentions)
alphamalex wrote in post #15304561
Does the print medium also matter? Should I ask them if they want to print on paper or canvas?
Generally speaking, some subjects are better suited for a specific print medium then others.
Also, sharpening tends to be different for different media. However, I suspect that the lab will take care of that aspect.