i've been using LR for noise reduction all along (only a couple out of thousands of photos, thanks to the superb sensor on my 5d2). while LR performs well most of the time, it sometimes smudges my photos even though i apply really light reduction on my iso6400 photos (i.e. 15/100 setting).
i was just curious how dedicated noise reduction plugins like nik Dfine - how do they perform in relation to LR?
Please try to stick to the topic as much as possible. thanks!

Also can try topaz denoise.
