This is the 3rd lens I have received new lately which has been decentered. All Canon zoom lenses.
With the latest purchase of a telephoto zoom and UWA zoom lens, I could see even through the viewfinder of the 6D that one side was soft. After a round of test photos in various conditions with IS on and off, it remained always the same. The 15-85 was the worst decentering I have ever seen, but this one is just bad enough to bug me. My 16-35II, while softer in the corners by design, is at least equal enough to my eye, that I can tell no difference.
When you get a new lens. Go outside in good light and get the camera on a tripod or high shutter speed like 1/2000 th. Find an object with sharp details, like a license plate, and shoot it from around 50-100 feet away with the lens stopped down a little. Put it in all 4 corners for 4 photos and then import them into photoshop, cut them and put the corners next to each other. It should be apparent which side is softer if any. Do this for several different setups just to make sure it isn't a fault in your testing.
Next, send it back to Canon if off center. 
I don't know if Canon has been slipping on QA lately or I just had bad luck. But in all the gear I have purchased in my life, I never had bad copies. Lately I have been sending faulty gear back way too often.
The black marks are to hide part of my neighbor's license plate. 
UWA = good to go! Even if soft in the corners, it is at least even, which is all I care about.
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Telephoto zoom = BAD! So bad I noticed it looking in the viewfinder before testing.
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