I have seen someone experiment with the number of exposures vs. exposure time (don't remember the site now), but I don't think I've seen the test you are talking about. But really you have your camera, why don't you do your own experiment? I also agree that 'hot pixel' noise is easy to remove in PP which would argue that you should just use the lowest ISO and longest time, but I have not had the best results doing this in night exposures.
If I remember correctly the conclusions that I have seen about taking 1 long exposure vs several shorter ones concluded that about 2min exposures were optimal - at least that is the ballpark figure I (think I) remember. Ideally you'd let the sensor cool down between exposures as well, but in reality once you get beyond a few minutes, even the moon can move significantly, so I just try to get the entire exposure done as quickly as possible and get as much light onto the sensor as possible. From night exposures I have taken, my gut feel is that 2-5 minutes is optimal - i.e set the ISO for that time frame - and then stack exposures if you can from there. I could be way of base, but this is what I have gravitated to with the 5DII.
Just as with HDR, several exposures can also help you choose how much exposure to apply to different parts of the image. For this reason alone I usually try to split up exposures of more than several minutes, so my estimate about could be biased my this.
I have also stacked short (1/15s) exposure shots taken at high ISO of a static subject (dark and needed a reasonable shutter speed). I put the camera in burst and took 6 shots in a burst, remove any with blur and stack the rest. It helped considerably. I had to be careful to do NR in the right order - I think I applied a bit pre-stack, but most post-stack. i know not really the question though.
So a long reply that doesn't answer your question, very useful of me
An interesting question though and one I would have thought would have had more of a general consensus of what to do. I might actually test this myself this weekend so I have more of a plan for my next night exposure, rather than winging it to a great extent.