Good replies here.
I recently sold a UT coded 16-35. Took very good care of it and mostly shot indoors. Lost a few hundred off new when selling it this year - a massively good value of like $4/mo. I was proud of what that lens has done and would continue to do, but worked hard to communicate all issues/concerns with the buyer, including a guarantee in case something happened. Bought a 50L with the proceeds. Was aware of the pre-2010 issue above and bought new. Love the new lens as much as the one it replaced.
The manufacturing of a given lens model doesn't really change over its production lifetime. And when the design changes, the name usually does too. Copy to copy consistency is as different month to month as year to year. What matters is what the lens goes through after the sale. Most are well built and most will show damage or mistreatment on the outside. So you get image samples and you get views of the outside and you balance the risk of what the lens may have been through against the reward of the savings (vs new).
Based on the buy/sell activity on POTN and the low incidents (I've yet to see one) of buyer dissatisfaction, results are hitting expectations everyday. Meanwhile, I've seen various complaints on new lenses, that are not yet field tested. Those are pretty good odds.