I should be clear here about 35mm digital vs. digital medium format:
1. In colors, both are very similar or closer, but MF has an edge, it could be that bigger sensor or better DR or more bit, is it 16bit vs. 12/14bit of 35mm?
2. Resolution, i mean pixel, i think here we can't talk about comparison, the largest mp 35mm camera are Sony/Nikon 36mp, i started digital medium format with 39mp and that was in 2009 if i remember, now i have 60mp, no comparison
3. Exposure DR, honestly speaking, MF has that since long time and most recent 35mm are coming closer, but if i we have to choose 1 winner then which best 35mm is on top than the best digital medium format? don't compare worse old medium format with latest high mp better DR, this is not comparison, this is just misleading, my best Canon and even my Sony A7R don't come close for highlight/shadow recovery against my H4D-60, the only thing with Canon and Sony are better is only cleaner recovery that's all.
4. Tonality or rendition, if we talk about colors then i said above about color, if about sharpness, mostly lenses are the key here, but if we put lens performance with sensor size and whatever another things, this must have a speak, even my normal lens of digital medium format which is HC 80mm giving me sharpness and tonal of skin color than not my best sharpest Canon Sony lens can produce, it come closer yes as i said, but never same or out-resolve, so if i have the choice between digital medium format and 35mm digital to shoot portraits under the light then i will always choose medium format even i can do amazing great with top line 35mm digital.
So, if we come to 35mm digital, the following are the mainly factors that give them advantages over digital medium format, not sure for how long but no doubt for long enough maybe:
1. Price, this is the first factor and i am sure if digital medium formats i mean brand news were around $10k or less, then i will see many medium formats in gear list of members online in many photography websites, and i will not see many jealous comments, even in 35mm that happen between expensive and affordable 35mm DSLR or mirrorless gear.
2. Weight, this is an issue for many shooters, all or most medium formats are bulky and big sizes, and many don't like this as daily use or travel or all-around shooting, so understandable.
3. AF speed, i am sure if that medium format has this ability against 35mm then we will see more shooter for MF, but i think even fastest AF MF is still way way beyond best AF 35mm DSLRs such as 1DX or 5D3 and so on.
4. High ISO, i can't remember one topic here or there when talking about newer 35mm digital without talking and showing about high ISO performance, even it makes me thinking as it is the only reason to buy the latest body due to best high ISO capability, but don't take me wrong, it is not the only reason, it is just my feeling about it.
5. FPS, for many shooters of sports, wildlife/ birds and so this is very handy, i know many will talk about timing, well, i used different cameras and i always get more keepers with higher fps cameras than slower one even both can be in same AF league, this is feature to use not to ignore it, if someone is a big master in timing then i hope to see all those SI or ESPN using film until now, they all used film in the past, why not keep using it, the question is, why they use top line of Canon/Nikon to shoot if they can do great with entry-level? i didn't see 7D or 7DII shooters anywhere in those pro sports shooter, even if they do i can guess it is 1% against 1 series or Nikon Dx gear.
6. Cocktail of lenses and accessories, yes, in medium format the most lenses for one system i can see is around 15 glasses if we talk about only manufacturer lenses, but if we talk about 3rd party or another brands to be used then even 35mm digital will lead here, if i can use 30 lenses with medium format then i can use over 100 for my 35mm digital, any objection here?
At the end, this is my opinion above about 35mm digital against digiMF, don't take my post as an accurate answers, you can correct me please or add, just don't joke much because i have wrong things, we all learn and we all have opinions, i may love MF a lot but many others may hate or disagree with that, so no need to make war about different points or opinions, if you have something to add or correct then let's do that politely, and when i say that it is because when i just recently replied[POSTed] in FB about something photographic, someone posted to show how wrong we are and he defended his points in so much way that we shouldn't talk again.
Comparison just for comparison can be done, but what is the purpose of it if it will not go anywhere? many agree about MF quality but still they can't buy it or use or afford it, then why ask for it, i can put my H4D-60 in test against all my Canon/sony gear, but at the end, what you gonna do with that or help you in what?
Sorry for my way of posting