When I bought it, I was told not to go cheap on the PSU. The CX750M wasn't exactly cheap so I didn't expect any problem. I took a lot of time to decide which CPU, GPU or CPU cooler to get, I didn't think too much when it came to the power supply. Clearly, I should have gone for something higher end like the SeaSonic you mention (which uses fans that only spin under heavy load).
It is also where most of the noise comes from, the fan is very noisy. I will change it eventually.
Boot times take a while mostly because the PC boots, then stops, then boots again. Most people with this motherboard have the same issue, I haven't found out how to correct it. It is not a huge deal but I'd rather have a PC that boots faster. On average it takes 45 seconds to reach the Desktop screen.
I'm still using Lightroom 5, perhaps Lightroom 6 would improve the overall performance as it uses the GPU for some of its tasks.
But now that you mention it, I have all my photos on the spinning hard drive. The SSD is used for the OS, some programs (including Lightroom) and my Adobe Premiere Pro sequence and files.
The plan is to change the power unit and to add another SSD but ultimately, I wonder whether money would be better spent towards buying an iMac down the road.
I'd make sure that the catalog and previews are moved to the SSD, your photos can be on the HDD but I can see from Luckless's post why hosting them on a SSD in the future would be a real advantage. Also a few of the things I do include:
1. Under Catalog Settings -> File handling make sure you pick a Standard Preview Size larger than the width of your screen (e.g., I have a 1920 x 122 display, so I set it to 2048). If you set it to something lower than your longest edge then it can take a long time for the displayed preview to appear "sharp".
2. I set my preview quality to High and discard 1:1's after 30 days:
- If I had a higher resolution monitor I'd pick Medium to reduce any performance hit from generating previews. I'd also pick Medium if I had a lower spec'd PC.
- If I was on a slow machine I'd probably also generate the 1:1's on import and take a bit of a hit on the time it takes to import images, where my current desktop is fast enough so I only generate standard previews on import.
3. Under Preferences -> File Handling I set the Camera RAW cache to a 25GB Max.
4. Camera Raw cache should be on your SSD, but I'd check just to make sure.
I hope some of this helps 


