Just picked up an M5 two days ago (currently traveling in Japan and picked one up tax-free with the 15-45mm kit lens). Haven't spent much time with photography in the past several years, but until I picked up this, I've used a 20D + BG-E2N battery grip with the 28-105mm f/3.5-4.5 as a walk-around and a reversed EF-S 18-55mm for macro shots. I caught wind of the M5 back in September, and was very interested. An SLR was too much to carry around, IMO, but I didn't want to sacrifice lens options or user-interface. By that I mean that shooting without at least two dedicated control dials is an absolute deal-breaker for me.
Granted the 20D (the body I'm coming from) is old and very out-of-date, I'm very satisfied so far. I will miss the comfort of a full-sized SLR with a battery-grip, but I can get used to the M5 for sure. The extra control dials are very nice, though I suppose that some of the newer pro-sumer/pro offerings aren't any different. It's nice having a dial I can dedicate to ISO (unlike the 20D). The on-sensor phase-detect AF is quite good, and the touch-and-drag feature works excellently. The EVF is alright (I haven't used an EVF before and it doesn't compare to an optical viewfinder, but I can get used to it). As with any SLR I get my hands on, I've changed the shutter half-press to enable AE, and set the rear "*" button to AF-activate. I disabled continuous AF on the M5, since I think it's very annoying. I haven't taken very many shots, and haven't processed any RAW images on a computer, but I'm satisfied with the previews on the camera so far 
The only gripe I have is the abysmal battery life... I think the main problem is that I'm used to an SLR, which you can leave in the "on" position with no problem (since it will automatically turn off until you half-press the shutter). The M5 is the same in that it will go to sleep when idle (I don't use the built-in ECO mode and instead opt to use a 15sec display off timer, and a 30sec sleep timer). The problem, however, is that the idle timer is broken by changes to the focus ring of the kit lens, switching between the EVF and the LCD, entering image review mode, etc. The first day, not realizing this, I left the camera on and it died on me before the end of the day (without taking more than 5 pictures!), I presume because as I was carrying it, the EVF/LCD sensor would change states, or the focus ring would be inadvertently shifted. Once the camera's in sleep mode, however, the only two things that turn it back on are a half-press of the shutter, or a press of the image review button. It would be nice to be able to press the M.Fn button (or any of the other assignable buttons) to instantly put the camera to sleep. At this point, I haven't figured out a better way to mitigate this problem, but for now I turned off auto-switching between the EVF/LCD (which eliminates the problem of breaking the idle timer by triggering the EVF sensor) and try not to bump the focus ring. Once I start using my EF lenses (which are at home), I don't think this will be a problem for me, but it's still a potential issue for any other STM EF-M lens (which I don't really plan on purchasing, so whatever). For the moment, I'm just trying to turn the camera off when I'm not using it. It boots quickly, so it hasn't been a problem, but I hope a future firmware update allows me to set a button to enter sleep mode directly, or perhaps setting the camera to only allow a half-press of the shutter break the idle timer.
I haven't tried the on-body flash (and probably won't really ever use it...), and haven't really played with any of the new-to-me features (videos, Wi-Fi/smartphone remote controls), but I don't expect to be using them very much anyhow (except for maybe 60fps 1080p videos).
Here's a sample cat picture from the M5 with the kit-lens that I took today. It was shot RAW, but since evidently the newest version of Lightroom (which I just bought and downloaded) doesn't support the M5 just yet (I assume, since it fails to preview any of them), I used the camera's built-in RAW processor to generate the JPG.
1/100 • f/6.3 • ISO 800
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