For the most part, the THX certification simply means that the speakers are capable of producing a certain frequency response range, and that the dispersion of the soundstage fits a certain pattern. Most respectable speakers would probably pass the THX test if they were subjected to the testing. It's mostly a marketing thing though. You'll notice that higher end speakers never carries THX certifications because the type of people that buy those speakers aren't going to be swayed by something like THX certifications.
With regards to mixing and matching brands, I wouldn't mix and match brands even if they both carry the same THX designation...even if two brands are THX certified, the timbre of the speakers can be completely different. i.e. Klipsch has a set of THX certified speakers and so does Polk audio. Klipsch is known to have a very bright character, whereas Polks are on the warmer side (relatively speaking). You really want to voice match your speakers as closely as possible so that the soundstage is consistent. At the very least your front speakers should be voice matched...you can get away with surrounds that aren't voice matched with your fronts though.




