Waited to install some updates to Windows 10 x64 (not the .1709 Fall Creators Update). Re-installed normally, tried running, no change. Ran under Administrator privileges, no change. Un-installed and then re-installed with Administrators privilege; still no difference, exits after about 5 seconds with no splash screen or top-level window.
Logged a support ticket yesterday with DXO, so far have not had any response beyond the automated BOT.
I'll wait until I install and test the Fall Creator's Update and then see if there is any change; I'll bet money there is some Windows .NET conflict that neither DXO nor Microsoft will be able to resolve (Microsoft has a long and sordid history of that with Windows 10).
The Mac version looks promising, did some test RAW conversions to compare to PhotoNinja and Affinity.



