The Lexar 1066x 64GB card is UDMA7 as I recall. When these first came out there were lots of issues and the final resolution was that the card reader had to be UDMA7 compatible. Lexar themselves, with their very high end reader, had to issue a firmware update to allow the reader to work reliably. You can read about the potential reader issue and incompatibility with UDMA7 at https://www.photo.net …xar-cards-failure.502098/
Check the camera firmware as well; for instance, with a 5DII firmware 2.1.2 incorporates a change that "Optimizes the camera’s performance when using certain UDMA 7-compatible CF cards released in February 2012 or later."
Checking around, some people report success in getting images off the card by leaving the card in the reader, then restarting their PC. If that works, don't touch the reader, use the opportunity to get the images off the card.
Also, before going much further, get yourself a bright flashlight and look into the card socket on the reader (or readers) and the camera. It has been awhile since much discussion of a bent pin in the socket but they have been know to happen and damage a card.
Thanks I tried the update but it stalls and it says it can't find the reader. pins are straight other cards work.
Lots of Bodies & Glass....

