I have never turned it off since 2006. An exception as a tripod and sometimes I'd forget but I don't use one that often. I had to with the 300 F4 iS as that generation did not auto detect no movement. I use with a monopod sometimes at 800mm and it helps.
The manuals warn about battery life and I can't see it not effecting it. Of course you can just change it. In one scenario my test showed it ran for 90 seconds and that was if the viewfinder did not detect something and start over. You would think that if it didn't run for all that extra time it would make a difference. There must a reason why there is a 2 second shut off with a DSLR.
I have read about and been long aware of IS and higher shutter speeds. I have not noticed a major negative effect as I always come home with plenty of keepers. Also that is what mode 3 is for. These were from my 2nd day out with my 7D and 300 F4 in 2009. I think the shutter speeds were around 1/5000 with IS on. People told me not to use it but I was getting my feet wet with BIF and just wanted to get the shots to build confidence.
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That being said I don’t disagree that IS can cause issues with initial AF and moving targets. This is based on what I had read. Turning it off is a good idea but I choose not to. Like I said that is what mode 3 is for.



