Pay attention to the vehicles your provider will use on safari, and how many people per vehicle. For my one trip, I was not on a photo-oriented tour, but the provider had arranged for us to be in vehicles with two people per row. I wouldn’t want more people than this, and I understand on many photography-oriented trips, they only have one person per row. Because of a foul up on one excursion we were stuck in big vehicles with four or five people per row, and it was miserable!
Especially for a once in a lifetime trip, I would try to have backup, not just one camera body. I’d prefer to have a backup telephoto lens as well, though that may not be possible for you. I hope it doesn’t get me thrown out of the club, but I took along a Sony RX10 with an absurd focal length range, and it was so convenient I tended to use it in preference to my full frame gear! It didn’t work well in dim lighting, though and there’s no shallow DOF available.
Don’t forget photos of the people and their culture! (sorry to go off-topic!
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