If he's taking a photo of a bug with a 400mm f/2.8, well... 
Seriously, it's all down to the lens. The longer telephotos let you still work from a further distance, as their MFD is longer to begin with AND some allow focusing well past infinity to begin with!
But, from experience, with any lens I'd be using with tubes to take a photo of a bug, (with the rare exception of a 100-400mm II and dragonflies) I'd likely not be able to focus that far away.
The best answer is in fact that one needs to either do the math, or test, for the specific lens in use as the results will vay WILDLY. Like dozens of yards difference from one lens to another.
I just was playing with the 50mm STM, and tubes, and the effective focus range was reduced to about 12" of leeway. ie: the closest I could focus and furthest I could focus were about 12 inches apart. In that case if the Deer was 3 feet away, it'd be too far to focus.