Hello: Yes I think it is possible. I use a similar Manfrotto unit mounted on a super clamp. The spigots on each end are tapped (1/4 on one end and 3/8 on the other) on the inside. A couple of ways to attach to a tripod would be:
1. Remove the tripod head from the tripod and attach the corresponding matching spigot (either 1/4 or 3/8) via a short threaded stud from the top of the tripod column to the spigot. This would completely eliminate the tripod head. Given the flexibility of the arm, this really should not be an issue. Most tripod heads are removable from the center columns (Check under the head for locking set screws prior to unscrewing)
2. Instead of replacing the tripod head, attach the spigot to the tripod's quick release plate via a 1/4 *20 threaded thumb screw. I would not recommend this solution as it would be really wobbly.
While I do not know the planned use, I've used my arm with a super clamp for close-up equipment photos and document copying with good results. If you can use the Super Clamp (or its knockoff) on a table, cart, or post in place of the tripod (a much better solution) provides a secure base. Just be sure to remember to tighten the knob attaching the spigot to the clamp (especially when using the arm upside down). Lets just say the gravity always works and can be expensive.
I had the advantage of using a smaller / lighter camera and lens combination (Canon M5 w/ 60 Macro). Whatever solution you use / come-up with, you will need to be very aware of camera shake (Remote release, Mirror lockup, Manual focus, ...) to ensure sharp photos.
Hopefully, these suggestions will help you solve your issue.
Any confusion or other issues, please feel free to contact me.