I have the f/4 beacuse of the size and weight. It's a fantastic lens that is reported to be every bit as sharp as the f/2.8 version, with some reviews saying it's sharper. Yes the AF can hunt in low light, like most lenses that are slower than f/2.8, but I use my outdoors during the day for 99% of my shots, so I've never had a problem.
f/4 1.56 lbs and 6.8" long
f/2.8 2.8 lbs and 7.6" long
f/2.8 IS 3.5 lbs and 7.7" long
If you don't mind heavy and cost isn't a factor I'd go for the IS version of the f/2.8, otherwise I'd go for the Sigma 70-200 f/2.8. If budget is your main concern, go for the f/4 or the Sigma, and if portability is what you want, go for the f/4. All excellent choices, you just have to decide for yourself.