It is quite easy for the manual focus ring to disengage the AF motor if parts of the body are loose. With what you said, I would worry about screws coming loose and possibly jamming the focusing. Since this is a prime, it is easier to take apart than a zoom. You will need a good set of JIS screwdrivers, a parts catalog for the lens and some knowledge of removing connectors properly. I can't recall but I think you will also need a lens spanner to take off the front ring to get access to the other side of the lens (disassembly from the rear only takes you so far and then you have to start at the front). Check the front filter ring to make sure there are no dents as this would hinder getting access. I would start from the rear since it will be much easier and see if that remedies the problem.
You should be able to re-tighten it and get more life out of it. You won't need to mess with any glass elements nor take off any parts like the AF motor. Also don't over tighten the screws, just snug them up. That way you don't risk damaging the screw heads which is the kiss of death for the lens. Lastly when loosening the screws, make sure to put force into the screw to keep the screwdriver seated into the screw as you turn it slowly to make sure it is loosening, again you don't want to go too fast and ruin the screw head.
Let me know if you need further details.