Well, I broke down today and ordered the 100-400 f/4-5.6L zoom. At first, I thought it would be an either/or situation, but it looks like I'm going to stick with both. I'll use the prime for strictly long shots, and I'll use the 100-400 for most of my everyday shooting. I know it's big, heavy, and not all that sharp on the long end, but it's a vast improvement over my 75-300, and fills the gap between 300 and 400mm. I'll lose that little bit between 75 and 100mm, but I have a 28-135 IS for that, and when (if) Dell ships my 70-300, I'll have L glass for everything up from 70 to 400mm.
I tried explaining all this to my wife to no avail. Just as well---she completely lost interest long before we had to discuss the money thing. When she got totally bored with the discussion, she just said, "Go ahead. Just get whatever you need. I'm going to bed"
These words will come back to haunt her---just as soon as the credit card statement arrives.