I believe that one of the ways to work quickest in Photoshop is to use the "quick keys" to select tools, commands, etc. There's a lot of them, but just try learning the 12 or 15 keys most used in digital photography. Learn them and use them and you'll fly through image editing.
Well, OK, maybe they're not a LOT faster - maybe they just seem it to me. But at the very least you get to look like a guru when someone's looking over your shoulder. 
Tools
C - Crop
J - Healing
L - Lasso
M - Marquee
S - Stamp (Clone)
W - Wand
Image Adjustments
Ctrl-L - Levels
Ctrl-M - Curves
Selections
Ctrl-D - Deselect All
Ctrl-Shift-I - Invert Selection
Zooming - Don't use the zoom tool - these are far better
Ctrl-0 - Fit on Screen (that's a zero)
Ctrl-Alt-0 - View 100%
Ctrl-+ - Zoom In (control-plus)
Ctrl-- - Zoom Out (control-minus)
Moving while Zoomed - My all time favorite
Hold Down Spacebar - Changes to Hand, click and drag to move image around
Getting Screen Space - My second favorite
Tab - Hide palettes and toolbar
Saving
Ctrl-Alt-Shift-S - Save for web
---What are they nuts? Am I an octopus?
Alt-F, W - Save for Web (Alt-F then W)
Alt-F, V - Save As
Alt-F, S - Save
Ctrl-S - Save (even better)
Well those are the ones that I use. Well, I actually don't use the Saving ones, but they seem handy, and the Ctrl-Alt-Shift-S is hysterical. My fingers hurt just thinking about it.

