I read something interesting and convincing on the web recently, but I just cannot find the link now. The upshot was, as I recall, that noise does not increase linearly (technically, monotonically) with ISO, but rather, there are periodic dips to lower noise than would be expected with a linear relationship. On most cameras, these dips are at ISO 100 200 400 800, etc. The explanation given was that these were the "real" sensitivities, while the intermediate settings being derived mathematically. Now - the interesting part is that for the 30D, these were at 160, 320, 640, 1250, etc.
I was convinced. I tend to use these steps now. I'll try to find the link, and post it if I have success.
Half an hour later - found it: link
and discussion
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There's more going on here than I understand, so decide for yourself if it's useful.