xarqi wrote in post #4306910
Earth just called - she wants her ozone layer back.
Earth just called - she wants her ozone layer back.
http://www.epa.gov …6/June/Day-04/pr-728.html
Relevant quotes:
1. 1,1-Difluoroethane has been designated by the EPA as a substance
about which it has little concern regarding its ozone-depleting
potential and is listed as an acceptable substitute for certain uses of
currently used ozone-depleting propellants. 1,1-Difluoroethane is now
used in consumer products (e.g., hair sprays, baby oil mousse, spray
bandage, rug shampoos and oven cleaners).
2. An acute rat toxicity study which showed no mortality when
animals were exposed to 1,1-difluoroethane at concentrations up to
200,000 ppm, indicating that the substance is essentially non-toxic
following acute inhalation exposure.
3. A chronic rat inhalation toxicity study with exposures for 6
hours, 5 days/week for 2 years, with a no-observed-effect-level (NOEL)
of 27,000 mg/M3 and LOEL of 67,500 mg/M3 based on mild
reversible renal effects.
4. A rat inhalation developmental toxicity study with pregnant CD
rats exposed to concentrations of 0, 5,000 or 50,000 ppm for 6 hours/
day on gestation days 6 through 15 showing no treatment-related
maternal or fetal effects at any dose level, indicating that 1,1-
difluoroethane is not a developmental toxicant at dose levels of equal
or less than 50,000 ppm.
5. A human (volunteers) study reported no adverse effects except
for reversible analgesia and feelings of impending loss of
consciousness after acute inhalation exposure to 500,000 ppm of 1,1-
difluoroethane.
6. 1,1-Difluoroethane is approved under 21 CFR 178.3010 by the
United States Food and Drug Administration (FDA) as an indirect food
additive (e.g., blowing agent in the production of polystyrene articles
which come in contact with food).
about which it has little concern regarding its ozone-depleting
potential and is listed as an acceptable substitute for certain uses of
currently used ozone-depleting propellants. 1,1-Difluoroethane is now
used in consumer products (e.g., hair sprays, baby oil mousse, spray
bandage, rug shampoos and oven cleaners).
2. An acute rat toxicity study which showed no mortality when
animals were exposed to 1,1-difluoroethane at concentrations up to
200,000 ppm, indicating that the substance is essentially non-toxic
following acute inhalation exposure.
3. A chronic rat inhalation toxicity study with exposures for 6
hours, 5 days/week for 2 years, with a no-observed-effect-level (NOEL)
of 27,000 mg/M3 and LOEL of 67,500 mg/M3 based on mild
reversible renal effects.
4. A rat inhalation developmental toxicity study with pregnant CD
rats exposed to concentrations of 0, 5,000 or 50,000 ppm for 6 hours/
day on gestation days 6 through 15 showing no treatment-related
maternal or fetal effects at any dose level, indicating that 1,1-
difluoroethane is not a developmental toxicant at dose levels of equal
or less than 50,000 ppm.
5. A human (volunteers) study reported no adverse effects except
for reversible analgesia and feelings of impending loss of
consciousness after acute inhalation exposure to 500,000 ppm of 1,1-
difluoroethane.
6. 1,1-Difluoroethane is approved under 21 CFR 178.3010 by the
United States Food and Drug Administration (FDA) as an indirect food
additive (e.g., blowing agent in the production of polystyrene articles
which come in contact with food).
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