Hi Jason,
It's a little difficult to give you an idea of settings. There are so many variables and the type of softbox used, it's efficiency, type of lighting, etc. play heavily in to it.
In terms of determining exposure I use a light meter. It eliminates the guess work completely. Once you have a reading you can then calculate alternate exposure settings based on the metered readings and can get very good at moving lighting or the subject and evaluating the exposure based on new distances or power levels, but this is always based on that first metering.
As a point of reference, in my studio, using a D-Lite 2 in a 36" x 48" softbox, placed 6 feet from the subject's face, at ISO 100 (I normally shoot ISO 200)......
Full power: f/8
Minimum power: f/2.0 + .2
Keep in mind that most often, and to get the best quality of light, you'd be working closer tot he subject and typically I would use a large diffusion panel for a full length shot, so the readings would be at least 1 stop higher. (2 stops if you factor in ISO 200)




