There is just no "one size fits all" answer on how large you can go. It is dependant on your image, how sharp is the original, how much noise is already there. I have printed as large as 30x40 off of a 20D file and the image was great at normal viewing distance. If you want to get up close to it and use a magnifying glass you will find issues. A print of this size will normally be viewed at 4 or 5 feet or more.
When I am working image to go to printing my normal process is to set the size in the crop options and then crop to the size I want and then sharpen to taste. If once I crop the image it is not what I want I will run Genuine Fractals against the original to see if it is any better than using the crop tool.
For an 11x14, assuming it is good to start with, you should be able to just use the crop tool. I would set the settings shown below.
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