Bill,
There are quite a few threads explaining that the lightsphere sucks and why. The best thing you can do for your photography flash-wise is work on knowing which direction to bounce your flash and why. Taking control of where the light goes and therefore where it appears to come from in the image will do wonders for your flash photography. The Lightsphere negates any control you can have over the direction of the flash's light by sending it in all directions. And because it sends light in all directions (illuminating things in that room that aren't even in the frame!), it wastes power. The bigger the room, the more the flash is going to struggle...and putting a Lightsphere on it makes it struggle even more.
(Ignoring portability) It's kind of like why a coach uses a megaphone instead of surround sound speakers during practice. He wants his voice to be sent directionally to the one he's yelling at, not everyone on the field.



