something worth mentioning I think, is that electronic equipment experiences both electrical and heat stress when powered on. That stress can be compared with a sack full of power-on hours. Certainly the balance is delicate between switching things on and off a couple of times a week to do backups, and leaving the damned thing on all the time.
The most likely time for a drive to fail will be at power-on time. That doesn't mean it won't fail anyway, just that leaving it off for two days, doesn't necessarily work in it's favour on day 3.
I've always thought the same thing. Generally speaking I'd rather leave a drive on all the time than regularly turn it off and on. If I turn it on once a month though for less than a days time I feel pretty comfortable that it has a decent chance of lasting a long time unless it gets mishandled, or is predisposed to early failure.
I could be wrong though, which is why I keep extra backups on extra hard drives 


