I bring greetings from the year 2017!
I found this thread while searching for information on the Domke F-3X, with all the usual questions of usability and will my gear fit and blah blah blah. This thread was a great help, so I just wanted to resurrect it for a moment to thank everybody for contributing to this great thread. A special thanks to Jim G for not only the excellent and well-illustrated review, but also for staying involved in the discussion for nearly five years! Thanks also to all the folks who shared their personal experiences and photos such as Jon, ANGUS, artspraken, 7dfever, zwright, jklewer, djchrono, and Rainyday. I'm sure there are others I omitted who deserve thanks as well, so apologies to anybody I missed and thanks to one and all!
I've always preferred small bags (my main bag for the past couple of years has been a Tamrac Rally 6), but I've been thinking about a larger bag lately and my recent acquisition of a grip for my 70D made it a necessity. I liked the F-3X in principle but I had a lot of questions about it and this thread has been a big help.
I picked one up today at my favorite local brick-and-mortar camera store, Ace Photo in Ashburn VA (one of the few remaining real camera stores in the DC area). They have a big room to one side, probably half of the sales floor, filled with rows and rows of bags from all of the well-known manufacturers. While the olive green and the RuggedWear brown both looked really sharp, I was going to get the sand color because I prefer light colors. However, they had two in tan, which I think is an older color, but I liked it so I got one of those. It's less brown than the sand color, more like khaki. Here it is:

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© mcoren [SHARE LINK] THIS IS A LOW QUALITY PREVIEW. Please log in to see the good quality stuff. Here is how I have it loaded now:
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© mcoren [SHARE LINK] THIS IS A LOW QUALITY PREVIEW. Please log in to see the good quality stuff. In the middle is the 70D + grip + Sigma 17-70. On the left is the Canon 70-200 f/4L, and on the right is the Canon 10-18 STM.
I also have a 430EX II flash in one of the side pockets, with plenty of room to spare. The other side pocket is currently empty, and I have my filters (grad ND + polarizer + Cokin P holder + rings) in the front pocket.
Thanks again to all!
Mike