TheSonofDarwin wrote in post #6915188
Try to answer your questions one by one.
Profile: CS4 is using my calibrated profile (see attached).
For which of the two screens is that profile? (I'm assuming a dual monitor setup)
The Acer I presume?
Can you check if PS and the OS agree on what monitor profile is used for what monitor?
Does the same thing happen with PS on the other screen (or the other screen as "main")?
TheSonofDarwin wrote in post #6915188
Mismatch: That synchronized thing doesn't really mean anything. Look at the attached image, now it says synchronized. If I click on "Ask when Opening" for the profile mismatches it changes that to unsynchronized.
Ah, okay. I assume you have CS3 set up different then? (Box unticked)
TheSonofDarwin wrote in post #6915188
Anything that isn't a straight preset (such as North American General Purpose 2) shows up as unsynchronized
Wait a sec...
You're saying that any "straight preset" shows as "syncronised", yet when you (un)tick a tickbox, it shows "unsynchronised"?
That's wrong... It should only say "Synchronised" when all Adobe applications are set up the same... I have CS2 and CS4 installed, and if I alter the color settings in one of them, it'll show as "unsynchronised", until I set both the same... (just tested it to make sure
)
TheSonofDarwin wrote in post #6915188
which is silly because asking for a prompt upon a mismatch doesn't change anything.
It gives you a choice, and a heads up. But I agree: I have all boxes ticked, except "mismatch".
The Acer is a wide Gamut? (Surprisingly difficult to find any meaningful specs on the web
)
TheSonofDarwin wrote in post #6915188
The result is the same on both, but I'm unsure that that matters because it'd only be me seeing the difference then.
Does this answer my "Does the same thing happen on the other screen" question?
Or do you mean the result shows the same on both?
I mean actually running the application on the other screen...
(Both PS and FF3. AFAIK Photoshop should identify the screen it's on, and use the correct profile (it did on my G4 with a dual screen setup). I think the same goes for FF3, but cannot test, since I'm nut running dual screen at the moment. Off course, all this might be different on Vista)
TheSonofDarwin wrote in post #6915188
Browser: On the screencast I showed 3 different browsers. Chrome, IE, and FF3 with color management enabled - the result was the same for all 3.
Oversaturated... Hmm. I'd expect that for a non color managed application on a screen with a wider gamut then the image has (sRGB). Not for FF3 however.
Check what FF thinks the monitor profile is. Maybe it thinks it's on the other screen...
TheSonofDarwin wrote in post #6915188
Saving: I've tried saving via Save for Web and via Save As with the same results, profile embedded for both. The only time when the result is normal is if I save as Adobe RGB.
That would indicate that your screen is wide gamut, and color management is off in the browsers...
TheSonofDarwin wrote in post #6915188
sRGB/sRGB: I know! That's what is driving me batty. It just doesn't make sense at all that the image would change going from sRGB to sRGB.
Indeed, it doesn't...
TheSonofDarwin wrote in post #6915188
Layers vs. Flattened: Damien brought up that suggestion earlier and I tried flattening the images first but that did not change anything either.
Hmm. Pity.
TheSonofDarwin wrote in post #6915188
Save for Web Preview: I have my save for web preview set as Use Document Profile. Should I set it to Monitor Profile? I noticed upon changing it to Monitor Profile with the same image that it is showing the messed up result. My profile is recently calibrated

"Use document profile" is (should be) color managed.
"Monitor profile" gives a preview of what the image will (should) look in a non color managed application on your monitor.
TheSonofDarwin wrote in post #6915188
Vista: Unfortunately, yes I'm using it.
Unfortunately, I don't have a PC running Vista. I'm curious as to what is happening here, but have no way to test 
I'm guessing that the dual monitor setup is somehow confusing either software or OS...
What is confusing is that CS3 did it right... Did anything else change?
Also: Check the CS3 color settings. With the same settings both applications should produce the same results. If they don't it's something to ask Adobe, 'cause it's likely a bug in CS4...