The popup is not particularly strong, but I would think at macro distances would be sufficient to get fill. When using flash outdoors in Av mode, the camera will automatically determine how much flash power is appropriate just for "fill" of a darkish/shadowy subject. As bohdank mentioned, take one shot and look at the result - then adjust flash exposure compensation wither up or down to increase or decrease the amount of fill the camera added.
Current: 5DM3, 6D, 8mm fish, 24-105/4IS, 35/2IS, 70-200/2.8IS, 85/1.8, 100-400/IS v1, lensbaby composer with edge 80, 580's and AB800's
Formerly: 80D, 7D, 300D, 5D, 5DM2, 20D, 50D, 1DM2, 17-55IS, 24-70/2.8, 28-135IS, 40/2.8, 50/1.8, 50/1.4, 70-200/4IS, 70-300IS, 70-200/2.8, 100 macro, 400/5.6, tammy 17-50 and 28-75, sigma 50 macro & 100-300