curlyq wrote:
but in manual focus it will mess it up, yes?
Yes, it can do. If the dioptric adjustment is set wrongly, and you're using manual focus, then it might seem to you that the picture is focussed properly when in fact it isn't. Or vice versa. Page 42 of your 350D's manual shows you how to set the dioptric adjustment, and it shows you where the "default" setting is (i.e. the right setting if your vision is good, or if you wear contact lenses or glasses when you take photos).
If you want to adjust the dioptric setting, the easiest way is probably to manually focus on infinity, look at a distant object, and tweak the dioptric until the subject looks sharp to you.
If you're having difficulty focussing, posting some sample pictures here - and telling us exactly what you did - would help.