I use the Lowepro Pro Runner x450. Its the right size for carry on luggage, can fit all my lenses and camera comfortably. It also carries my 15.4 inch laptop (It even comes with a latop sleeve, but I still use my Crumpler). Its handy for difficult terrain because it has retractable back-pack straps and its handy for air travel because it has wheels and the retractable tow handle. Also it has the Lowepro weatherproof jacket that folds out over the bag. The camera section is extra deep so that it can pack most extra large lenses.
All in all I think its a great all rounder.
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Here's the link to the Lowepro Website: http://products.lowepro.com …unner-x450-AW,2186,16.htm






